Advances in targeting central sensitization and brain plasticity in chronic pain

نویسندگان

چکیده

Abstract Maladaptation in sensory neural plasticity of nociceptive pathways is associated with various types chronic pain through central sensitization and remodeling brain connectivity. Within this context, extensive research has been conducted to evaluate the mechanisms efficacy certain non-pharmacological treatment modalities. These include neurostimulation, virtual reality, cognitive therapy rehabilitation. Here, we summarize involved review novel findings relation desensitization modulation for management intractable prevention acute-to-chronic transition.

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ژورنال

عنوان ژورنال: The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

سال: 2022

ISSN: ['1687-8329', '1110-1083']

DOI: https://doi.org/10.1186/s41983-022-00472-y